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BIO NMDCAT Ribonucleic acid (RNA)
nmdcat.online July 3, 2026

77. The removal of the terminal phosphate group from the 5′ end of a pre-mRNA would directly disrupt

A. The attachment of the 7-methylguanosine cap
✓
B. The addition of the 3' poly-A tail
C. The excision of the final structural intron
D. The formation of internal hairpin loops

📝 Explanation

Capping enzymes require the 5' triphosphate terminal structure of the nascent RNA transcript to successfully link the inverted guanosine cap.

📖 Additional Information

  • The attachment of the 7-methylguanosine cap
  • The addition of the 3' poly-A tail
  • The excision of the final structural intron
  • The formation of internal hairpin loops

Capping enzymes require the 5' triphosphate terminal structure of the nascent RNA transcript to successfully link the inverted guanosine cap.

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