98. The occurrence of a genetic defect that selectively inactivates the mannose-6-phosphate receptor in an animal cell line results in the constitutive secretion of newly synthesized acid hydrolases out of the cell. This condition demonstrates that the primary destination for these enzymes should have been the
A.
Matrix of active mitochondria
B.
Internal lumen of the lysosome
✓
C.
Hydrophilic core of the chloroplast
D.
Central vacuole of the cell
📝 Explanation
The mannose-6-phosphate tag acts as a molecular sorting signal that targets newly built hydrolytic enzymes to the lysosome.
📖 Additional Information
Matrix of active mitochondria
Internal lumen of the lysosome
Hydrophilic core of the chloroplast
Central vacuole of the cell
The mannose-6-phosphate tag acts as a molecular sorting signal that targets newly built hydrolytic enzymes to the lysosome.
