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BIO NMDCAT ENZYMES
nmdcat.online July 11, 2026

Among the following, the correct statement regarding the conversion of an apoenzyme to a holoenzyme is that it

A. Requires the removal of a prosthetic group by dialysis
B. Is a reversible process involving the binding of a specific cofactor
✓
C. Involves an irreversible proteolytic cleavage
D. Results in a complete change in the substrate specificity

📝 Explanation

An inactive apoenzyme becomes an active holoenzyme upon binding its required cofactor, a non-covalent, reversible process essential for regulation.

📖 Additional Information

  • Requires the removal of a prosthetic group by dialysis
  • Is a reversible process involving the binding of a specific cofactor
  • Involves an irreversible proteolytic cleavage
  • Results in a complete change in the substrate specificity

An inactive apoenzyme becomes an active holoenzyme upon binding its required cofactor, a non-covalent, reversible process essential for regulation.

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