BIO NMDCAT Sexually transmitted diseases
nmdcat.online July 16, 2026

Following the application of penicillin for the treatment of early syphilis, a patient may experience fever, chills, and muscle aches due to the rapid lysis of spirochetes and release of endotoxin-like molecules. This temporary physiological response is known as:

A. Anaphylactic shock
B. Jarisch-Herxheimer reaction
C. Autoimmune cascade
D. Type IV hypersensitivity

📝 Explanation

The correct option is Jarisch-Herxheimer reaction. This is a classic reaction occurring within hours of antibiotic treatment for spirochetal infections, caused by the massive release of antigens from dying bacteria triggering a strong inflammatory response.

📖 Additional Information

  • Anaphylactic shock
  • Jarisch-Herxheimer reaction
  • Autoimmune cascade
  • Type IV hypersensitivity

The correct option is Jarisch-Herxheimer reaction. This is a classic reaction occurring within hours of antibiotic treatment for spirochetal infections, caused by the massive release of antigens from dying bacteria triggering a strong inflammatory response.

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