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nmdcat.online July 11, 2026

For an enzyme that follows Michaelis-Menten kinetics, a low Km value indicates that the enzyme

A. Has a high turnover number for the reaction
B. Requires a low concentration of substrate to reach half-maximal velocity
✓
C. Is inhibited by low concentrations of the product
D. Achieves Vmax only at very high substrate concentrations

📝 Explanation

Km is the substrate concentration at half of Vmax. A low Km indicates high affinity, requiring only a low concentration to reach effective catalytic rates.

📖 Additional Information

  • Has a high turnover number for the reaction
  • Requires a low concentration of substrate to reach half-maximal velocity
  • Is inhibited by low concentrations of the product
  • Achieves Vmax only at very high substrate concentrations

Km is the substrate concentration at half of Vmax. A low Km indicates high affinity, requiring only a low concentration to reach effective catalytic rates.

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