BIO NMDCAT Factors that Affect the Rate of Enzyme Reactions
nmdcat.online July 11, 2026

In an experiment, an enzyme shows maximum activity at pH 8.0 and greatly reduced activity at pH 5.0. The most appropriate explanation is

A. The substrate is absent at pH 5.0
B. Catalytic amino acid residues become improperly ionized at pH 5.0
C. Enzyme concentration decreases automatically
D. The enzyme changes into another protein

📝 Explanation

Changes in pH alter the ionization of amino acid side chains, affecting substrate binding and catalytic function.

📖 Additional Information

  • The substrate is absent at pH 5.0
  • Catalytic amino acid residues become improperly ionized at pH 5.0
  • Enzyme concentration decreases automatically
  • The enzyme changes into another protein

Changes in pH alter the ionization of amino acid side chains, affecting substrate binding and catalytic function.

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