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nmdcat.online July 11, 2026

In living organisms, metabolic pathways are compartmentalized (e.g., citric acid cycle enzymes in the mitochondria). This primarily serves to

A. Prevent the enzymes from being digested by lysosomal proteases
B. Segregate opposing metabolic pathways and increase the local concentration of substrates and enzymes
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C. Allow the enzymes to function at a pH much higher than the cytosol
D. Ensure that all enzymes in the pathway are synthesized as a single polyprotein

📝 Explanation

Compartmentalization separates catabolic and anabolic pathways to prevent futile cycles and concentrates reactants to increase reaction efficiency.

📖 Additional Information

  • Prevent the enzymes from being digested by lysosomal proteases
  • Segregate opposing metabolic pathways and increase the local concentration of substrates and enzymes
  • Allow the enzymes to function at a pH much higher than the cytosol
  • Ensure that all enzymes in the pathway are synthesized as a single polyprotein

Compartmentalization separates catabolic and anabolic pathways to prevent futile cycles and concentrates reactants to increase reaction efficiency.

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