BIO NMDCAT Factors that Affect the Rate of Enzyme Reactions

nmdcat.online July 11, 2026

The decline in enzyme activity beyond the optimum temperature is primarily associated with

A. Reduced kinetic energy of molecules

B. Irreversible alteration of the active site's three-dimensional structure

✓

C. Increased substrate concentration

D. Greater enzyme synthesis

📝 Explanation

Excessive heat disrupts hydrogen bonds and hydrophobic interactions, leading to denaturation and loss of catalytic activity.

📖 Additional Information

Reduced kinetic energy of molecules
Irreversible alteration of the active site's three-dimensional structure
Increased substrate concentration
Greater enzyme synthesis

Excessive heat disrupts hydrogen bonds and hydrophobic interactions, leading to denaturation and loss of catalytic activity.

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