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nmdcat.online July 11, 2026

The most appropriate explanation for the high turnover number of carbonic anhydrase is that

A. It binds its substrate, CO₂, with very low affinity
B. The activation energy for the reaction without the enzyme is negligible
C. The reaction rate is essentially diffusion-limited
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D. It is an allosteric enzyme

📝 Explanation

Carbonic anhydrase is so efficient that the rate-limiting step is the diffusion of the substrate into the active site.

📖 Additional Information

  • It binds its substrate, CO₂, with very low affinity
  • The activation energy for the reaction without the enzyme is negligible
  • The reaction rate is essentially diffusion-limited
  • It is an allosteric enzyme

Carbonic anhydrase is so efficient that the rate-limiting step is the diffusion of the substrate into the active site.

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