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nmdcat.online June 27, 2026

The primary difference between α-D-glucose and β-D-glucose is the orientation of the hydroxyl group attached to the

A. 1st carbon atom
✓
B. 4th carbon atom
C. 6th carbon atom
D. 5th carbon atom

📝 Explanation

When glucose forms a ring, carbon 1 becomes an asymmetric carbon (the anomeric carbon). In the α-anomer, the -OH on C1 is below the plane of the ring (trans to the CH2OH at C5). In the β-anomer, the -OH is above the plane of the ring (cis to the CH2OH).

📖 Additional Information

  • 1st carbon atom
  • 4th carbon atom
  • 6th carbon atom
  • 5th carbon atom

When glucose forms a ring, carbon 1 becomes an asymmetric carbon (the anomeric carbon). In the α-anomer, the -OH on C1 is below the plane of the ring (trans to the CH2OH at C5). In the β-anomer, the -OH is above the plane of the ring (cis to the CH2OH).

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