BIO NMDCAT Neurons
nmdcat.online July 7, 2026

The rapid enzymatic breakdown of acetylcholine in the synaptic cleft is accomplished by

A. Monoamine oxidase
B. Catechol-O-methyltransferase
C. Acetylcholinesterase
D. ATP diphosphohydrolase

📝 Explanation

Acetylcholinesterase (AChE) is the enzyme located in the synaptic cleft that rapidly hydrolyzes ACh into acetate and choline, terminating the synaptic signal to prevent continuous stimulation.

📖 Additional Information

  • Monoamine oxidase
  • Catechol-O-methyltransferase
  • Acetylcholinesterase
  • ATP diphosphohydrolase

Acetylcholinesterase (AChE) is the enzyme located in the synaptic cleft that rapidly hydrolyzes ACh into acetate and choline, terminating the synaptic signal to prevent continuous stimulation.

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