The reaction mechanism of lysozyme involves the distortion of a sugar ring into a strained “sofa” conformation. This illustrates the catalytic strategy of
A.
Providing a macroenvironment that neutralizes all charges on the substrate
B.
Using covalent catalysis to form a stable enzyme substrate intermediate
C.
Preferentially binding and stabilizing the transition state of the reaction
✓
D.
Lowering the pH of the bulk solution to non specifically hydrolyze the substrate
📖 Additional Information
Providing a macroenvironment that neutralizes all charges on the substrate
Using covalent catalysis to form a stable enzyme substrate intermediate
Preferentially binding and stabilizing the transition state of the reaction
Lowering the pH of the bulk solution to non specifically hydrolyze the substrate
