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Pathophysiology-II

197 questions found

Practice Questions

31. A patient with severe rheumatoid arthritis (RA) develops joint deformities and systemic symptoms. From a technical pathophysiological perspective, RA is characterized by:

A. Degeneration of articular cartilage.
B. Autoimmune inflammation of the synovial membrane.
C. Deposition of uric acid crystals.
D. Bacterial infection of the joint.
nmdcat.online BS Nursing
Jun 6, 2026

32. A patient with chronic heart failure experiences pulmonary edema. What is the technical primary pathophysiological mechanism causing the fluid accumulation in the lungs?

A. Decreased oncotic pressure.
B. Increased hydrostatic pressure in the pulmonary capillaries due to left ventricular dysfunction.
C. Increased lymphatic drainage.
D. Decreased capillary permeability.
nmdcat.online BS Nursing
Jun 6, 2026

18. A patient with untreated hypothyroidism presents with cold intolerance, constipation, fatigue, and bradycardia. What is the technical primary pathophysiological cause of these symptoms?

A. Increased metabolic rate.
B. Decreased production of thyroid hormones, leading to a generalized hypometabolic state.
C. Autoimmune destruction of the adrenal glands.
D. Excess growth hormone.
nmdcat.online BS Nursing
Jun 6, 2026

20. A patient with advanced Alzheimer’s disease exhibits progressive memory loss, cognitive decline, and behavioral changes. From a clinical perspective, what is the critical underlying neuro-pathophysiological process?

A. Loss of dopaminergic neurons.
B. Accumulation of amyloid plaques and neurofibrillary tangles.
C. Demyelination of nerve fibers.
D. Increased cerebrospinal fluid pressure.
nmdcat.online BS Nursing
Jun 6, 2026

21. A patient with long-standing Type 2 Diabetes Mellitus develops numbness, tingling, and burning pain in his feet. What is the technical primary pathophysiological basis for diabetic neuropathy?

A. Acute inflammation of nerve endings.
B. Demyelination due to autoimmune attack.
C. Microvascular damage and metabolic alterations affecting nerve fibers.
D. Compression of spinal nerves.
nmdcat.online BS Nursing
Jun 6, 2026

23. A patient with a severe allergic reaction (anaphylaxis) presents with widespread urticaria, angioedema, bronchospasm, and hypotension. What is the technical primary mediator responsible for these symptoms?

A. Complement activation.
B. Autoantibody production.
C. Massive release of histamine and other inflammatory mediators from mast cells and basophils.
D. T-cell mediated cytotoxicity.
nmdcat.online BS Nursing
Jun 6, 2026

24. A patient with severe trauma develops rhabdomyolysis. What is the technical pathophysiological consequence of rhabdomyolysis on the kidneys?

A. Glomerular hyperfiltration.
B. Direct tubular damage from myoglobin casts.
C. Increased erythropoietin production.
D. Renal artery stenosis.
nmdcat.online BS Nursing
Jun 6, 2026

25. A patient with chronic heart failure is prescribed a loop diuretic (e.g., Furosemide). From a medicinal perspective, what is the technical pathophysiological mechanism by which this drug reduces fluid overload?

A. Increases reabsorption of sodium and water.
B. Blocks aldosterone receptors.
C. Inhibits sodium and chloride reabsorption in the loop of Henle, leading to increased diuresis.
D. Decreases heart rate.
nmdcat.online BS Nursing
Jun 6, 2026

12. A 60-year-old chronic alcoholic presents with jaundice, ascites, and variceal bleeding. What is the technical primary pathophysiological consequence of liver cirrhosis leading to these symptoms?

A. Impaired glucose metabolism.
B. Portal hypertension and hepatocellular dysfunction.
C. Renal tubular damage.
D. Increased bile production.
nmdcat.online BS Nursing
Jun 6, 2026
nmdcat.online BS Nursing
Jun 6, 2026

14. A patient with hypertension is prescribed an ACE inhibitor. From a medicinal perspective, what is the technical pathophysiological mechanism by which this drug lowers blood pressure?

A. Directly relaxes vascular smooth muscle.
B. Increases sodium reabsorption in the kidneys.
C. Blocks the conversion of angiotensin I to angiotensin II, reducing vasoconstriction and aldosterone secretion.
D. Stimulates sympathetic nervous system.
nmdcat.online BS Nursing
Jun 6, 2026

16. A patient with systemic lupus erythematosus (SLE) develops facial rash, joint pain, and proteinuria. From a technical pathophysiological view, SLE is characterized by:

A. T-cell mediated destruction of tissues.
B. Autoantibody production and immune complex deposition.
C. IgE-mediated hypersensitivity reaction.
D. Non-inflammatory joint degeneration.
nmdcat.online BS Nursing
Jun 6, 2026

6. A 40-year-old woman develops a sudden, severe headache, nuchal rigidity, fever, and altered mental status. Lumbar puncture reveals purulent CSF with high protein, low glucose, and elevated WBC count (neutrophils). What is the critical medicinal implication of these findings?

A. Viral meningitis, requiring symptomatic treatment.
B. Bacterial meningitis, requiring urgent broad-spectrum antibiotics.
C. Subarachnoid hemorrhage, requiring surgical consultation.
D. Migraine headache, requiring analgesics.
nmdcat.online BS Nursing
Jun 6, 2026

7. A patient with chronic kidney disease (CKD) experiences progressive anemia. From a technical pathophysiological perspective, what is the primary reason for this anemia in CKD?

A. Iron deficiency.
B. Vitamin B12 deficiency.
C. Decreased production of erythropoietin by the kidneys.
D. Increased red blood cell destruction.
nmdcat.online BS Nursing
Jun 6, 2026
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