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Pathophysiology-II

197 questions found

Practice Questions

92. A patient with a history of chronic kidney disease on dialysis develops bone pain and fractures. What is the technical primary pathophysiological mechanism causing renal osteodystrophy?

A. Increased Vitamin D production.
B. Impaired phosphate excretion, leading to hyperphosphatemia, hypocalcemia, and secondary hyperparathyroidism.
C. Increased calcium absorption.
D. Decreased parathyroid hormone.
nmdcat.online BS Nursing
Jun 6, 2026

76. A patient with severe sepsis develops acute respiratory distress syndrome (ARDS). What is the technical primary pathophysiological change in ARDS?

A. Bronchoconstriction.
B. Non-cardiogenic pulmonary edema due to increased alveolar-capillary membrane permeability.
C. Alveolar destruction.
D. Pulmonary fibrosis.
nmdcat.online BS Nursing
Jun 6, 2026

93. A patient with a sudden onset of vision loss, severe headache, and pain on chewing, along with an elevated ESR, is suspected of having giant cell arteritis. What is the critical urgency for medicinal intervention?

A. To prescribe oral antibiotics.
B. Immediate high-dose corticosteroids to prevent permanent vision loss.
C. To observe and monitor symptoms.
D. To perform immediate surgery.
nmdcat.online BS Nursing
Jun 6, 2026

77. A patient with a history of long-standing hypertension develops a hemorrhagic stroke. What is the technical primary pathophysiological cause of hemorrhagic stroke in this context?

A. Thromboembolic event.
B. Rupture of a cerebral blood vessel (often due to weakened walls from chronic hypertension).
C. Vasospasm.
D. Global cerebral ischemia.
nmdcat.online BS Nursing
Jun 6, 2026

78. A patient with acute appendicitis presents with right lower quadrant pain, rebound tenderness, and fever. What is the critical clinical urgency in managing this condition?

A. Oral antibiotics and observation.
B. Surgical appendectomy to prevent perforation and peritonitis.
C. Laxatives.
D. Pain medication only.
nmdcat.online BS Nursing
Jun 6, 2026

95. A patient with a history of heavy smoking develops recurrent pneumonia in the same lung segment. What is the critical clinical concern in this scenario?

A. Fungal infection.
B. Underlying lung cancer obstructing the airway.
C. Autoimmune disease.
D. Chronic bronchitis.
nmdcat.online BS Nursing
Jun 6, 2026

79. A patient with chronic heart failure is prescribed spironolactone. From a medicinal perspective, what is the technical pathophysiological mechanism of spironolactone?

A. Loop diuretic.
B. Aldosterone antagonist, reducing sodium and water retention and potassium loss.
C. Beta-blocker.
D. ACE inhibitor.
nmdcat.online BS Nursing
Jun 6, 2026

80. A patient with a history of valvular heart disease develops infective endocarditis. What is the technical primary pathophysiological process?

A. Autoimmune inflammation of the heart valves.
B. Bacterial colonization and vegetation formation on damaged heart valves.
C. Degeneration of heart valve tissue.
D. Increased pressure in the heart chambers.
nmdcat.online BS Nursing
Jun 6, 2026

65. A patient with acute pyelonephritis presents with fever, chills, flank pain, and dysuria. What is the technical primary pathophysiological event?

A. Viral infection of the bladder.
B. Bacterial infection and inflammation of the renal parenchyma and renal pelvis.
C. Kidney stone obstruction.
D. Glomerular inflammation.
nmdcat.online BS Nursing
Jun 6, 2026

66. A patient with severe heart failure develops cardiogenic shock. What is the technical primary pathophysiological event in cardiogenic shock?

A. Increased systemic vascular resistance.
B. Profound decrease in cardiac output, leading to inadequate tissue perfusion.
C. Increased blood volume.
D. Vasodilation.
nmdcat.online BS Nursing
Jun 6, 2026

67. A patient with chronic heart failure experiences worsening dyspnea on exertion and orthopnea. What is the technical pathophysiological mechanism driving the orthopnea?

A. Peripheral vasoconstriction.
B. Redistribution of fluid from the lower extremities to the pulmonary circulation when lying flat.
C. Decreased venous return.
D. Increased cardiac contractility.
nmdcat.online BS Nursing
Jun 6, 2026

68. A patient with a history of chronic alcoholism develops acute onset of delirium tremens. What is the critical clinical urgency in managing this condition?

A. Administering oral fluids.
B. Monitoring for and managing seizures, arrhythmias, and severe agitation with benzodiazepines.
C. Encouraging sleep.
D. Providing nutritional supplements.
nmdcat.online BS Nursing
Jun 6, 2026

69. A patient with a history of deep vein thrombosis (DVT) is prescribed a direct oral anticoagulant (DOAC) like rivaroxaban. From a medicinal perspective, what is the technical pathophysiological mechanism of rivaroxaban?

A. Inhibits Vitamin K epoxide reductase.
B. Directly inhibits Factor Xa.
C. Directly inhibits thrombin.
D. Binds to antithrombin III.
nmdcat.online BS Nursing
Jun 6, 2026

70. A patient with hyperthyroidism presents with weight loss, heat intolerance, tremors, and tachycardia. What is the technical primary pathophysiological cause?

A. Decreased thyroid hormone production.
B. Excess thyroid hormone production, leading to a generalized hypermetabolic state.
C. Adrenal insufficiency.
D. Excess parathyroid hormone.
nmdcat.online BS Nursing
Jun 6, 2026

71. A patient with Crohn’s disease develops intestinal strictures and fistulas. What is the technical pathophysiological process leading to these complications?

A. Superficial mucosal inflammation.
B. Transmural inflammation and fibrosis.
C. Diverticular outpouchings.
D. Gastric acid erosion.
nmdcat.online BS Nursing
Jun 6, 2026

72. A patient with a history of chronic kidney disease develops metabolic acidosis. What is the technical primary pathophysiological reason for this?

A. Increased bicarbonate reabsorption.
B. Impaired renal excretion of acid and reduced bicarbonate regeneration.
C. Overproduction of lactic acid.
D. Excessive loss of CO2?.
nmdcat.online BS Nursing
Jun 6, 2026

73. A patient with a suspected subarachnoid hemorrhage presents with sudden “thunderclap” headache, nuchal rigidity, and photophobia. What is the urgent clinical action required based on the likely pathophysiology?

A. Oral analgesics.
B. Immediate neuroimaging to confirm hemorrhage and neurosurgical consultation.
C. Physical therapy.
D. Antihistamines.
nmdcat.online BS Nursing
Jun 6, 2026

74. A patient with severe anemia (Hb 5 g/dL) presents with pallor, fatigue, and dyspnea on exertion. What is the technical primary pathophysiological consequence of severe anemia?

A. Increased oxygen-carrying capacity.
B. Decreased oxygen-carrying capacity of the blood, leading to tissue hypoxia.
C. Increased blood viscosity.
D. Enhanced immune response.
nmdcat.online BS Nursing
Jun 6, 2026
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