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Pathophysiology-II

197 questions found

Practice Questions

116. A patient with acute pancreatitis develops systemic complications like acute respiratory distress syndrome (ARDS) and renal failure. What is the critical underlying pathophysiological mechanism?

A. Localized inflammation.
B. Systemic inflammatory response to pancreatic enzymes, leading to widespread organ damage.
C. Hypovolemia.
D. Infection.
nmdcat.online BS Nursing
Jun 6, 2026

117. A patient with hypovolemic shock (e.g., from severe hemorrhage) presents with hypotension, tachycardia, and cool, clammy skin. What is the technical primary pathophysiological mechanism causing these signs?

A. Vasodilation.
B. Decreased intravascular volume, leading to reduced preload, cardiac output, and tissue perfusion.
C. Increased cardiac contractility.
D. Increased systemic vascular resistance.
nmdcat.online BS Nursing
Jun 6, 2026

118. A patient with uncompensated metabolic alkalosis has high blood pH and high bicarbonate. What is the technical primary pathophysiological cause of the alkalosis?

A. Hyperventilation.
B. Increased bicarbonate levels (e.g., due to vomiting or diuretic use) or excessive acid loss.
C. Decreased production of lactic acid.
D. Excessive loss of CO2?.
nmdcat.online BS Nursing
Jun 6, 2026

119. A patient with acute kidney injury is diagnosed with post-renal AKI. What is the technical primary pathophysiological cause?

A. Reduced renal perfusion.
B. Direct damage to kidney tubules.
C. Obstruction of urinary outflow from the kidneys.
D. Glomerular inflammation.
nmdcat.online BS Nursing
Jun 6, 2026

120. A patient with severe pneumonia develops septic shock. What is the urgent clinical medicinal intervention required for septic shock?

A. Oral antibiotics and observation.
B. Immediate administration of broad-spectrum antibiotics, intravenous fluids, and vasopressors to restore tissue perfusion.
C. Oral steroids.
D. Oxygen therapy only.
nmdcat.online BS Nursing
Jun 6, 2026

121. A patient with a history of Gout experiences acute joint pain, swelling, and redness in the big toe. What is the technical primary pathophysiological mechanism of gout?

A. Autoimmune inflammation.
B. Deposition of uric acid crystals in the joint, leading to an inflammatory response.
C. Bacterial infection.
D. Degeneration of articular cartilage.
nmdcat.online BS Nursing
Jun 6, 2026

122. A patient with chronic heart failure experiences cardiac remodeling (ventricular hypertrophy and dilation). What is the technical pathophysiological consequence of this remodeling on cardiac function?

A. Improved cardiac output.
B. Increased myocardial oxygen demand and impaired contractility, leading to progressive worsening of heart failure.
C. Decreased preload.
D. Enhanced relaxation.
nmdcat.online BS Nursing
Jun 6, 2026

123. A patient with an acute stroke presents within the thrombolytic window. What is the critical clinical urgency for medicinal intervention if no contraindications exist?

A. To delay treatment until full recovery.
B. Immediate assessment for eligibility for thrombolytic therapy (tPA) to restore blood flow and minimize brain damage.
C. To administer antiplatelet agents only.
D. To observe and monitor.
nmdcat.online BS Nursing
Jun 6, 2026

124. A patient with chronic kidney disease (CKD) develops fluid overload. What is the technical primary pathophysiological reason for this?

A. Increased renal filtration.
B. Impaired renal excretion of sodium and water.
C. Decreased fluid intake.
D. Increased protein intake.
nmdcat.online BS Nursing
Jun 6, 2026

125. A patient with a history of deep vein thrombosis (DVT) on anticoagulation develops sudden onset of abdominal pain and hematochezia. What is the critical clinical concern?

A. Appendicitis.
B. Anticoagulant-associated gastrointestinal bleeding.
C. Diverticulitis.
D. Irritable bowel syndrome.
nmdcat.online BS Nursing
Jun 6, 2026

111. A patient with a history of recurrent urinary tract infections (UTIs) develops fever, chills, and flank pain. What is the critical clinical urgency in recognizing these symptoms?

A. To treat symptomatic UTI.
B. To identify and urgently treat pyelonephritis (kidney infection) to prevent sepsis and kidney damage.
C. To advise increased fluid intake.
D. To perform a urinalysis.
nmdcat.online BS Nursing
Jun 6, 2026

112. A patient with a spinal cord injury develops autonomic dysreflexia. What is the technical primary pathophysiological cause?

A. Loss of motor function.
B. Exaggerated sympathetic response to noxious stimuli below the level of injury, due to impaired autonomic regulation.
C. Peripheral nerve damage.
D. Brainstem compression.
nmdcat.online BS Nursing
Jun 6, 2026

113. A patient with uncompensated respiratory alkalosis (e.g., due to hyperventilation) has high blood pH and low PCO2?. What is the technical primary pathophysiological cause of the alkalosis?

A. Decreased production of lactic acid.
B. Excessive elimination of CO2? from the lungs.
C. Increased bicarbonate reabsorption.
D. Overproduction of ketone bodies.
nmdcat.online BS Nursing
Jun 6, 2026

114. A patient with an acute ischemic stroke receives tissue plasminogen activator (tPA). From a medicinal perspective, what is the technical pathophysiological mechanism of tPA?

A. Decreases blood pressure.
B. Breaks down fibrin clots, restoring blood flow to ischemic brain tissue.
C. Prevents platelet aggregation.
D. Increases cerebral blood flow by vasodilation.
nmdcat.online BS Nursing
Jun 6, 2026

98. A patient with hyperkalemia from acute kidney injury is administered insulin with glucose. From a medicinal perspective, what is the technical pathophysiological mechanism of this intervention?

A. Increases potassium excretion.
B. Drives potassium intracellularly.
C. Blocks potassium channels.
D. Promotes potassium reabsorption.
nmdcat.online BS Nursing
Jun 6, 2026

99. A patient with acute onset of severe, crushing chest pain, diaphoresis, and shortness of breath is in the emergency room. ECG shows ST-segment elevation. What is the critical urgency for medicinal intervention?

A. Administering oral antibiotics.
B. Immediate reperfusion therapy (fibrinolysis or PCI) for acute myocardial infarction.
C. Administering pain medication only.
D. Encouraging rest.
nmdcat.online BS Nursing
Jun 6, 2026

100. A patient with asthma is exposed to an allergen and develops an acute exacerbation. What is the technical primary pathophysiological response that leads to bronchoconstriction?

A. Increased production of surfactant.
B. IgE-mediated mast cell degranulation and release of bronchoconstrictive mediators (e.g., histamine, leukotrienes).
C. Activation of macrophages.
D. Inhibition of smooth muscle contraction.
nmdcat.online BS Nursing
Jun 6, 2026

101. A patient with a history of liver cirrhosis develops spontaneous bacterial peritonitis (SBP). What is the technical primary pathophysiological mechanism?

A. Fungal infection of the peritoneum.
B. Translocation of gut bacteria into the ascitic fluid.
C. Viral infection.
D. Autoimmune inflammation.
nmdcat.online BS Nursing
Jun 6, 2026

102. A patient with a history of long-standing hypertension develops hypertensive urgency/emergency. What is the critical clinical urgency in managing this condition?

A. To lower blood pressure slowly over days.
B. To reduce blood pressure promptly but carefully to prevent end-organ damage.
C. To administer oral diuretics only.
D. To observe without intervention.
nmdcat.online BS Nursing
Jun 6, 2026
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