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Pathophysiology-II

197 questions found

Practice Questions

103. A patient with Cushing’s syndrome develops osteoporosis. What is the technical primary pathophysiological cause of this complication?

A. Decreased calcium absorption.
B. Excess cortisol leading to increased bone resorption and decreased bone formation.
C. Vitamin D deficiency.
D. Increased estrogen levels.
nmdcat.online BS Nursing
Jun 6, 2026

105. A patient with chronic heart failure has an ejection fraction of 30%. What is the technical primary pathophysiological implication of this reduced ejection fraction?

A. Diastolic dysfunction.
B. Impaired systolic function and reduced cardiac output.
C. Increased preload.
D. Normal cardiac function.
nmdcat.online BS Nursing
Jun 6, 2026

106. A patient with peptic ulcer disease experiences sudden, severe abdominal pain that is relieved by antacids. What is the technical primary pathophysiological cause of peptic ulcer pain?

A. Inflammation of the pancreas.
B. Erosion of the gastric or duodenal mucosa by acid and pepsin.
C. Bowel obstruction.
D. Appendicitis.
nmdcat.online BS Nursing
Jun 6, 2026

107. A patient with severe anemia due to chronic blood loss presents with compensatory tachycardia and increased cardiac output. What is the technical primary pathophysiological rationale for these cardiovascular adaptations?

A. To increase blood viscosity.
B. To maintain tissue oxygen delivery despite reduced oxygen-carrying capacity.
C. To decrease cardiac workload.
D. To increase red blood cell production.
nmdcat.online BS Nursing
Jun 6, 2026

108. A patient with a history of atrial fibrillation on warfarin presents with severe gastrointestinal bleeding. What is the urgent clinical medicinal action required?

A. To administer more warfarin.
B. Immediate reversal of anticoagulation with Vitamin K and/or fresh frozen plasma (FFP).
C. To administer aspirin.
D. To observe the bleeding.
nmdcat.online BS Nursing
Jun 6, 2026

109. A patient with chronic kidney disease develops pruritus (itching). What is the technical primary pathophysiological reason for this?

A. Allergic reaction.
B. Accumulation of uremic toxins.
C. Fungal infection.
D. Dry skin.
nmdcat.online BS Nursing
Jun 6, 2026

110. A patient with acute glomerulonephritis presents with hematuria, proteinuria, and edema. What is the technical primary pathophysiological event in acute glomerulonephritis?

A. Tubular damage.
B. Inflammation of the glomeruli, leading to increased permeability and impaired filtration.
C. Obstruction of the urinary tract.
D. Renal artery stenosis.
nmdcat.online BS Nursing
Jun 6, 2026

96. A patient with Systemic Inflammatory Response Syndrome (SIRS) progresses to multiple organ dysfunction syndrome (MODS). What is the technical underlying pathophysiological mechanism of MODS?

A. Localized inflammation.
B. Uncontrolled systemic inflammation leading to widespread endothelial injury, organ dysfunction, and failure.
C. Hypovolemia.
D. Nutritional deficiency.
nmdcat.online BS Nursing
Jun 6, 2026

97. A patient with diabetes develops proliferative retinopathy. What is the technical primary pathophysiological mechanism?

A. Inflammation of the retina.
B. Neovascularization (new blood vessel growth) due to chronic ischemia and hypoxia.
C. Detachment of the retina.
D. Increased intraocular pressure.
nmdcat.online BS Nursing
Jun 6, 2026

81. A patient with uncompensated metabolic acidosis has low blood pH and low bicarbonate. What is the technical primary pathophysiological cause of the acidosis?

A. Hyperventilation.
B. Increased production or decreased excretion of metabolic acids.
C. Overproduction of CO2?.
D. Excessive loss of chloride.
nmdcat.online BS Nursing
Jun 6, 2026

82. A patient with acute cholecystitis presents with severe right upper quadrant pain, fever, and nausea. What is the technical primary pathophysiological event?

A. Pancreatic inflammation.
B. Gallstone obstruction of the cystic duct, leading to inflammation of the gallbladder.
C. Gastric ulceration.
D. Appendicitis.
nmdcat.online BS Nursing
Jun 6, 2026

83. A patient with a history of stroke develops post-stroke spasticity. From a technical pathophysiological perspective, spasticity is caused by:

A. Loss of muscle strength.
B. Damage to upper motor neurons, leading to increased muscle tone and hyperreflexia.
C. Peripheral nerve damage.
D. Muscle atrophy.
nmdcat.online BS Nursing
Jun 6, 2026

84. A patient with a large pleural effusion presents with dyspnea and diminished breath sounds over the affected lung. What is the technical primary pathophysiological reason for the dyspnea?

A. Bronchospasm.
B. Compression of the lung by fluid in the pleural space, limiting lung expansion.
C. Alveolar inflammation.
D. Pulmonary embolism.
nmdcat.online BS Nursing
Jun 6, 2026

86. A patient with iron deficiency anemia presents with pallor, fatigue, and spoon-shaped nails (koilonychia). What is the technical primary pathophysiological cause of the anemia?

A. Impaired red blood cell production due to insufficient iron for hemoglobin synthesis.
B. Increased red blood cell destruction.
C. Vitamin B12 deficiency.
D. Bone marrow failure.
nmdcat.online BS Nursing
Jun 6, 2026

87. A patient with diverticulitis presents with left lower quadrant pain, fever, and leukocytosis. What is the technical primary pathophysiological event?

A. Inflammation of diverticula (outpouchings) in the colon, often due to fecal impaction.
B. Gastric ulceration.
C. Appendicitis.
D. Inflammatory bowel disease.
nmdcat.online BS Nursing
Jun 6, 2026

88. A patient with acute kidney injury is diagnosed with pre-renal azotemia. What is the technical primary pathophysiological cause?

A. Obstruction of the urinary tract.
B. Reduced renal perfusion (e.g., due to hypovolemia or decreased cardiac output).
C. Direct damage to kidney tubules.
D. Glomerular inflammation.
nmdcat.online BS Nursing
Jun 6, 2026

89. A patient with Parkinson’s disease experiences tremors, rigidity, bradykinesia, and postural instability. What is the technical primary pathophysiological defect?

A. Accumulation of amyloid plaques.
B. Loss of dopaminergic neurons in the substantia nigra.
C. Demyelination of nerve fibers.
D. Increased acetylcholine production.
nmdcat.online BS Nursing
Jun 6, 2026

90. A patient with severe asthma exacerbation presents with profound dyspnea, wheezing, and use of accessory muscles. What is the urgent clinical medicinal intervention required?

A. Oral steroids.
B. Immediate administration of inhaled short-acting beta-agonists and systemic corticosteroids.
C. Oral antibiotics.
D. Nasal decongestants.
nmdcat.online BS Nursing
Jun 6, 2026

91. A patient with left-sided heart failure develops peripheral edema. What is the technical primary pathophysiological mechanism causing the peripheral edema?

A. Increased plasma oncotic pressure.
B. Increased systemic venous pressure due to right ventricular failure, or fluid retention secondary to left-sided failure.
C. Decreased capillary permeability.
D. Decreased hydrostatic pressure.
nmdcat.online BS Nursing
Jun 6, 2026
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