BIO NMDCAT Chromosomes
nmdcat.online July 4, 2026

6. The histone protein acting as a linker component to seal the DNA ribbon outside the core nucleosome particle is

A. Histone H1
B. Histone H2A
C. Histone H3
D. Histone H4

📝 Explanation

Histone H1 is distinct from the core octamer proteins; it functions as the linker histone that binds to the entry/exit site of DNA on the nucleosome core particle, facilitating higher-order folding into the 30-nm solenoid fiber.

📖 Additional Information

  • Histone H1
  • Histone H2A
  • Histone H3
  • Histone H4

Histone H1 is distinct from the core octamer proteins; it functions as the linker histone that binds to the entry/exit site of DNA on the nucleosome core particle, facilitating higher-order folding into the 30-nm solenoid fiber.

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