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BIO NMDCAT Conjugated molecules
nmdcat.online July 3, 2026

60. The chemical nature of the linkage connecting the lipid anchor to the carbohydrate core in a glycosylphosphatidylinositol (GPI)-anchored protein is a

A. Phosphodiester and covalent bond framework
✓
B. Reversible non-covalent hydrogen bond attraction
C. Purely ionic interaction between magnesium ions
D. Direct peptide linkage between fatty acids and sugars

📝 Explanation

GPI anchors use a complex bridge made of a phospholipid linked via a phosphodiester bond to an oligosaccharide, which then binds the protein.

📖 Additional Information

  • Phosphodiester and covalent bond framework
  • Reversible non-covalent hydrogen bond attraction
  • Purely ionic interaction between magnesium ions
  • Direct peptide linkage between fatty acids and sugars

GPI anchors use a complex bridge made of a phospholipid linked via a phosphodiester bond to an oligosaccharide, which then binds the protein.

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