BIO NMDCAT Conjugated molecules
nmdcat.online July 3, 2026

87. A researcher isolates a novel lipid-anchored protein from a mammalian cell membrane and determines that it is released from the membrane upon treatment with the enzyme phosphatidylinositol-specific phospholipase C (PI-PLC). This observation proves that the protein is a

A. Lipopolysaccharide variant
B. Glycosylphosphatidylinositol (GPI)-anchored glycoprotein
C. Core histone nucleoprotein complex
D. Chylomicron apolipoprotein component

📝 Explanation

PI-PLC specifically hydrolyzes the phosphodiester bond within the GPI anchor, releasing the attached glycoprotein from its lipid tail.

📖 Additional Information

  • Lipopolysaccharide variant
  • Glycosylphosphatidylinositol (GPI)-anchored glycoprotein
  • Core histone nucleoprotein complex
  • Chylomicron apolipoprotein component

PI-PLC specifically hydrolyzes the phosphodiester bond within the GPI anchor, releasing the attached glycoprotein from its lipid tail.

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