nmdcat.online
BIO NMDCAT Ribonucleic acid (RNA)
nmdcat.online July 3, 2026

92. The selective inhibition of the enzyme poly-A polymerase in a eukaryotic cell line would lead to the accumulation of cytoplasmic transcripts that are

A. Structurally normal but restricted to the nucleolus
B. Highly unstable and rapidly degraded by exonucleases
✓
C. Incapable of undergoing alternative splicing mechanisms
D. Selectively translated at abnormally accelerated rates

📝 Explanation

Without a protective 3' poly-A tail, newly exported cytoplasmic mRNA molecules are quickly targeted and broken down by cellular exonucleases.

📖 Additional Information

  • Structurally normal but restricted to the nucleolus
  • Highly unstable and rapidly degraded by exonucleases
  • Incapable of undergoing alternative splicing mechanisms
  • Selectively translated at abnormally accelerated rates

Without a protective 3' poly-A tail, newly exported cytoplasmic mRNA molecules are quickly targeted and broken down by cellular exonucleases.

🔗 Share This Question

Facebook Twitter LinkedIn WhatsApp

🧭 Navigate Questions

Previous Question

91. An analysis of a eukaryotic gene reveals that it produces a single pre-mRNA transcript, but three distinct tissue-specific proteins are detected. This structural variation is most likely achieved by

Next Question

93. During the process of transcription elongation, the temporary RNA-DNA hybrid helix within the transcription bubble adopts a structural geometry that is

Back to All Questions

🔗 Related MCQs

Concerning the duration of muscle twitches, if a skeletal muscle twitch lasts approximately 10-100 milliseconds, what is the expected duration of a typical smooth muscle contraction?
July 28, 2026
The physiological response to hypoxia (low oxygen) differs among muscle types. Which muscle type is most susceptible to irreversible damage following a brief period of hypoxia?
July 28, 2026
A medical relevance of understanding muscle tissue differences is the development of calcium channel blockers. These drugs are primarily used to treat hypertension (high blood pressure) and angina. They exert their biological effect mainly by acting on:
July 28, 2026
During the process of cell differentiation, which muscle type loses its ability to divide and form new cells almost completely, relying solely on hypertrophy for growth?
July 28, 2026
The functional relationship between the shape of a muscle cell and its tissue type is evident when observing spindle-shaped cells. This specific morphology allows the cells to:
July 28, 2026

Categories

View all →