BIO NMDCAT Sexually transmitted diseases
nmdcat.online July 16, 2026

A 30-year-old female experiences recurrent episodes of small, painful blisters on her genitalia. She notes that these outbreaks often occur during periods of high physiological stress. The physiological response triggering the recurrence is related to:

A. Spontaneous bacterial generation in the vesicles
B. Reactivation of latent virus migrating down sensory nerves
C. Hormonal stimulation of new viral infections
D. Secondary bacterial infection of old scars

📝 Explanation

The correct option is Reactivation of latent virus migrating down sensory nerves. Stress temporarily weakens the immune system, allowing latent HSV residing in the sensory ganglia to reactivate, travel anterograde down the axon, and cause new lesions on the epithelium.

📖 Additional Information

  • Spontaneous bacterial generation in the vesicles
  • Reactivation of latent virus migrating down sensory nerves
  • Hormonal stimulation of new viral infections
  • Secondary bacterial infection of old scars

The correct option is Reactivation of latent virus migrating down sensory nerves. Stress temporarily weakens the immune system, allowing latent HSV residing in the sensory ganglia to reactivate, travel anterograde down the axon, and cause new lesions on the epithelium.

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