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BIO NMDCAT Sexually transmitted diseases
nmdcat.online July 16, 2026

In HIV pathogenesis, the viral enzyme reverse transcriptase plays a crucial role. The pharmacological inhibition of this enzyme directly prevents the:

A. Attachment of the virus to the CD4 receptor
B. Synthesis of viral DNA from the viral RNA genome
✓
C. Integration of viral DNA into the host genome
D. Assembly and budding of new virions

📝 Explanation

The correct option is Synthesis of viral DNA from the viral RNA genome. Reverse transcriptase is responsible for converting the single-stranded viral RNA into double-stranded proviral DNA. Inhibiting it stops viral replication at this step.

📖 Additional Information

  • Attachment of the virus to the CD4 receptor
  • Synthesis of viral DNA from the viral RNA genome
  • Integration of viral DNA into the host genome
  • Assembly and budding of new virions

The correct option is Synthesis of viral DNA from the viral RNA genome. Reverse transcriptase is responsible for converting the single-stranded viral RNA into double-stranded proviral DNA. Inhibiting it stops viral replication at this step.

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