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BIO NMDCAT Sexually transmitted diseases
nmdcat.online July 16, 2026

A biological comparison between the primary lesions of syphilis and genital herpes reveals that while the syphilitic chancre is highly infectious and painless, the herpes vesicle is:

A. Non-infectious and painless
B. Highly infectious and extremely painful
✓
C. Non-infectious and deeply indurated
D. Precancerous and hard

📝 Explanation

The correct option is Highly infectious and extremely painful. A primary clinical distinction is that herpes lesions (vesicles and shallow ulcers) are highly infectious and notoriously painful, whereas the syphilitic chancre is typically solitary, infectious, and painless.

📖 Additional Information

  • Non-infectious and painless
  • Highly infectious and extremely painful
  • Non-infectious and deeply indurated
  • Precancerous and hard

The correct option is Highly infectious and extremely painful. A primary clinical distinction is that herpes lesions (vesicles and shallow ulcers) are highly infectious and notoriously painful, whereas the syphilitic chancre is typically solitary, infectious, and painless.

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