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BIO NMDCAT Sexually transmitted diseases
nmdcat.online July 16, 2026

In females, gonococcal infection most frequently initiates in the epithelial lining of the cervix rather than the vagina. The biological reason for this tissue tropism is that Neisseria gonorrhoeae preferentially infects:

A. Stratified squamous epithelium
B. Columnar epithelial cells
✓
C. Smooth muscle cells
D. Endothelial cells

📝 Explanation

The correct option is Columnar epithelial cells. N. gonorrhoeae specifically targets and adheres to columnar and transitional epithelium (found in the cervix and urethra). The adult vagina is lined with stratified squamous epithelium, which resists gonococcal attachment.

📖 Additional Information

  • Stratified squamous epithelium
  • Columnar epithelial cells
  • Smooth muscle cells
  • Endothelial cells

The correct option is Columnar epithelial cells. N. gonorrhoeae specifically targets and adheres to columnar and transitional epithelium (found in the cervix and urethra). The adult vagina is lined with stratified squamous epithelium, which resists gonococcal attachment.

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