BIO NMDCAT Sexually transmitted diseases
nmdcat.online July 16, 2026

A patient is treated for gonorrhea with a standard antibiotic regimen but returns two weeks later with persistent urethritis. Assuming medication compliance and no reinfection, the most scientifically valid explanation is:

A. The pathogen developed latency in the nervous system.
B. The pathogen was intrinsically a virus resistant to antibiotics.
C. The infection involved a penicillinase-producing or drug-resistant strain.
D. The antibiotic caused a secondary autoimmune reaction.

📝 Explanation

The correct option is The infection involved a penicillinase-producing or drug-resistant strain. Neisseria gonorrhoeae is notorious for acquiring antibiotic resistance mechanisms, such as plasmids carrying penicillinase, making standard therapies ineffective and requiring alternative drug regimens.

📖 Additional Information

  • The pathogen developed latency in the nervous system.
  • The pathogen was intrinsically a virus resistant to antibiotics.
  • The infection involved a penicillinase-producing or drug-resistant strain.
  • The antibiotic caused a secondary autoimmune reaction.

The correct option is The infection involved a penicillinase-producing or drug-resistant strain. Neisseria gonorrhoeae is notorious for acquiring antibiotic resistance mechanisms, such as plasmids carrying penicillinase, making standard therapies ineffective and requiring alternative drug regimens.

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