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nmdcat.online June 27, 2026

In the induced fit model, the substrate binding to the enzyme’s active site induces a conformational change that results in the

A. Release of a water molecule, breaking the substrate
B. Proper alignment of catalytic residues for the reaction
✓
C. Permanent binding of the substrate to the enzyme
D. Unfolding of the enzyme's secondary structure

📝 Explanation

The conformational change in the induced fit model positions the essential catalytic amino acid side chains in the precise orientation needed to perform chemistry on the substrate. This is in addition to the strain and proximity effects also associated with the model.

📖 Additional Information

  • Release of a water molecule, breaking the substrate
  • Proper alignment of catalytic residues for the reaction
  • Permanent binding of the substrate to the enzyme
  • Unfolding of the enzyme's secondary structure

The conformational change in the induced fit model positions the essential catalytic amino acid side chains in the precise orientation needed to perform chemistry on the substrate. This is in addition to the strain and proximity effects also associated with the model.

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