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BIO NMDCAT Sexually transmitted diseases
nmdcat.online July 16, 2026

The human immunodeficiency virus (HIV) is sexually transmitted and progressively compromises the host’s immune system. The profound immunodeficiency primarily results from the viral targeting and destruction of:

A. B lymphocytes
B. Erythrocytes
C. CD4+ T-helper lymphocytes
✓
D. Cytotoxic T cells (CD8+)

📝 Explanation

The correct option is CD4+ T-helper lymphocytes. HIV uses the CD4 receptor to enter and eventually destroy T-helper cells. The loss of these orchestrator cells severely impairs both humoral and cell-mediated immune responses, leading to AIDS.

📖 Additional Information

  • B lymphocytes
  • Erythrocytes
  • CD4+ T-helper lymphocytes
  • Cytotoxic T cells (CD8+)

The correct option is CD4+ T-helper lymphocytes. HIV uses the CD4 receptor to enter and eventually destroy T-helper cells. The loss of these orchestrator cells severely impairs both humoral and cell-mediated immune responses, leading to AIDS.

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