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BIO NMDCAT Sexually transmitted diseases
nmdcat.online July 16, 2026

The physiological mechanism by which Neisseria gonorrhoeae evades mucosal immunity involves the secretion of a specific enzyme that cleaves and inactivates the predominant antibody found in mucosal secretions. This targeted antibody is:

A. IgE
B. IgM
C. IgA
✓
D. IgG

📝 Explanation

The correct option is IgA. IgA is the principal antibody class protecting mucosal surfaces. N. gonorrhoeae secretes IgA1 protease, which cleaves the antibody, neutralizing the host's localized mucosal immune defense and allowing colonization.

📖 Additional Information

  • IgE
  • IgM
  • IgA
  • IgG

The correct option is IgA. IgA is the principal antibody class protecting mucosal surfaces. N. gonorrhoeae secretes IgA1 protease, which cleaves the antibody, neutralizing the host's localized mucosal immune defense and allowing colonization.

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