B.
To urgently recommend revising or replacing the outcome measure to ensure reliable and valid data collection, crucial for the integrity of the results. ✓
B.
To urgently consider the implications of low power (high risk of Type II error) and the need for a larger, adequately powered trial before discarding a potentially beneficial therapy. ✓
C.
To fund a smaller, less expensive trial. ✓
D.
To rely solely on the current non-significant p-value. ✓
