Practice Questions

180. A patient with severe sepsis develops disseminated intravascular coagulation (DIC). What is the technical primary pathophysiological feature of DIC?

A. Localized clot formation.
B. Widespread activation of coagulation and fibrinolysis, leading to simultaneous thrombosis and bleeding.
C. Platelet destruction only.
D. Hemolysis.
nmdcat.online BS Nursing
Jun 6, 2026

179. A patient with chronic liver disease develops portal hypertension. What is the technical primary pathophysiological cause of portal hypertension in cirrhosis?

A. Increased blood flow to the liver.
B. Increased resistance to blood flow through the cirrhotic liver.
C. Decreased cardiac output.
D. Increased systemic blood pressure.
nmdcat.online BS Nursing
Jun 6, 2026

178. A patient with a history of valvular heart disease develops acute onset of shortness of breath and an S3 gallop. What is the critical clinical urgency in identifying the cause of this acute decompensation?

A. To rule out pneumonia.
B. To identify acute exacerbation of heart failure, often due to valvular dysfunction, requiring urgent medical management.
C. To assess for DVT.
D. To evaluate for allergic reaction.
nmdcat.online BS Nursing
Jun 6, 2026

177. A patient with acute kidney injury is diagnosed with pre-renal AKI. What is the critical clinical urgency in managing this condition?

A. To immediately start dialysis.
B. To identify and urgently correct the underlying cause of hypoperfusion (e.g., fluid resuscitation, improving cardiac output).
C. To administer loop diuretics.
D. To prescribe antibiotics.
nmdcat.online BS Nursing
Jun 6, 2026

176. A patient with a peptic ulcer is prescribed a proton pump inhibitor (PPI). From a medicinal perspective, what is the technical pathophysiological mechanism of PPIs?

A. Neutralizes gastric acid.
B. Irreversibly blocks the H+/K+-ATPase pump in gastric parietal cells, reducing acid secretion.
C. Forms a protective barrier over the ulcer.
D. Increases mucus production.
nmdcat.online BS Nursing
Jun 6, 2026

175. A patient with chronic obstructive pulmonary disease (COPD) develops peripheral edema and jugular venous distension. What is the technical primary pathophysiological cause of these signs in COPD?

A. Left-sided heart failure.
B. Cor pulmonale (right-sided heart failure due to pulmonary hypertension).
C. Renal failure.
D. Liver cirrhosis.
nmdcat.online BS Nursing
Jun 6, 2026

174. A patient with an acute allergic reaction (anaphylaxis) is administered epinephrine. From a medicinal perspective, what is the technical primary pathophysiological mechanism of epinephrine in anaphylaxis?

A. Antihistamine effect.
B. Vasoconstriction, bronchodilation, and decreased mediator release from mast cells.
C. Corticosteroid effect.
D. Direct mast cell stabilization.
nmdcat.online BS Nursing
Jun 6, 2026

173. A patient with a history of recurrent urinary tract infections (UTIs) presents with fever, chills, and flank pain. What is the critical clinical concern in recognizing these symptoms?

A. Lower UTI.
B. Pyelonephritis (upper UTI), requiring urgent antibiotic treatment to prevent kidney damage and sepsis.
C. Viral infection.
D. Kidney stone.
nmdcat.online BS Nursing
Jun 6, 2026

172. A patient with severe pneumonia and hypoxemia is placed on mechanical ventilation. What is the technical primary pathophysiological goal of mechanical ventilation in this context?

A. To increase spontaneous breathing.
B. To improve alveolar ventilation and oxygenation, and reduce the work of breathing.
C. To cause bronchoconstriction.
D. To prevent fluid accumulation.
nmdcat.online BS Nursing
Jun 6, 2026

171. A patient with adrenal insufficiency (Addison’s disease) develops hyperkalemia. What is the technical primary pathophysiological reason for this?

A. Excess cortisol.
B. Aldosterone deficiency, leading to impaired renal potassium excretion.
C. Increased potassium intake.
D. Decreased renin.
nmdcat.online BS Nursing
Jun 6, 2026
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