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BIO NMDCAT Sexually transmitted diseases
nmdcat.online July 16, 2026

In the context of maternal-fetal transmission, a pregnant woman with active genital herpes lesions at the time of onset of labor is typically advised to undergo a cesarean section. The primary biological rationale for this intervention is to prevent:

A. Transplacental infection of the fetal nervous system
B. Neonatal exposure to the virus during passage through the birth canal
✓
C. Premature rupture of amniotic membranes
D. Development of congenital syphilis in the newborn

📝 Explanation

The correct option is Neonatal exposure to the virus during passage through the birth canal. Genital herpes is generally not transmitted across the placenta (unlike syphilis). Neonatal herpes is acquired via direct contact with infectious lesions in the birth canal, which a C-section bypasses.

📖 Additional Information

  • Transplacental infection of the fetal nervous system
  • Neonatal exposure to the virus during passage through the birth canal
  • Premature rupture of amniotic membranes
  • Development of congenital syphilis in the newborn

The correct option is Neonatal exposure to the virus during passage through the birth canal. Genital herpes is generally not transmitted across the placenta (unlike syphilis). Neonatal herpes is acquired via direct contact with infectious lesions in the birth canal, which a C-section bypasses.

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Regarding viral sexually transmitted diseases, which of the following pathogens establishes lifelong latency in the sacral sensory ganglia and causes recurrent outbreaks of painful vesicular lesions?

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