MCQs

11142 questions found

Practice Questions

57. A patient with severe sepsis develops acute kidney injury. What is the critical underlying pathophysiological mechanism of AKI in sepsis?

A. Prerenal azotemia due to hypovolemia.
B. Postrenal obstruction.
C. Acute tubular necrosis (ATN) due to renal hypoperfusion and inflammatory mediators.
D. Glomerulonephritis.
nmdcat.online BS Nursing
Jun 6, 2026

56. A patient with cirrhosis develops esophageal varices. What is the technical primary pathophysiological mechanism leading to variceal formation?

A. Decreased synthetic function of the liver.
B. Portal hypertension, causing collateral circulation and dilation of esophageal veins.
C. Inflammation of the esophagus.
D. Gastric acid reflux.
nmdcat.online BS Nursing
Jun 6, 2026

55. A medicinal approach to managing hypertension involves a calcium channel blocker. What is the technical primary pathophysiological mechanism of action of this drug class?

A. Blocks beta-adrenergic receptors.
B. Inhibits angiotensin-converting enzyme.
C. Blocks calcium influx into vascular smooth muscle and cardiac cells, leading to vasodilation and reduced cardiac contractility.
D. Increases sodium excretion.
nmdcat.online BS Nursing
Jun 6, 2026

54. A patient with uncompensated respiratory acidosis (e.g., due to severe COPD exacerbation) has low blood pH and high PCO2?. What is the technical primary pathophysiological cause of the acidosis?

A. Excessive production of lactic acid.
B. Impaired alveolar ventilation and CO2? retention.
C. Loss of bicarbonate from the kidneys.
D. Overproduction of ketone bodies.
nmdcat.online BS Nursing
Jun 6, 2026

53. A patient with Cushing’s syndrome presents with central obesity, moon facies, buffalo hump, and striae. What is the technical primary pathophysiological cause of these clinical manifestations?

A. Adrenal insufficiency.
B. Excess glucocorticoid (cortisol) production.
C. Excess aldosterone production.
D. Thyroid hormone deficiency.
nmdcat.online BS Nursing
Jun 6, 2026

52. A patient with acute kidney injury (AKI) presents with oliguria, elevated creatinine, and electrolyte imbalances. From a clinical perspective, what is the urgency in determining the cause of AKI?

A. To identify the underlying cause (pre-renal, intra-renal, post-renal) to guide urgent specific management.
B. To immediately start dialysis.
C. To administer large volumes of fluids.
D. To prescribe antibiotics.
nmdcat.online BS Nursing
Jun 6, 2026

51. A patient with a history of alcohol abuse develops acute pancreatitis. What is the technical primary pathophysiological event leading to the inflammation?

A. Autoimmune attack on the pancreas.
B. Obstruction of the pancreatic duct by a gallstone.
C. Premature activation of digestive enzymes within the pancreas.
D. Bacterial infection.
nmdcat.online BS Nursing
Jun 6, 2026

50. A patient with a history of atherosclerosis develops angina pectoris. What is the technical primary pathophysiological mechanism causing the chest pain?

A. Myocardial cell necrosis.
B. Imbalance between myocardial oxygen supply and demand.
C. Pericardial inflammation.
D. Esophageal spasm.
nmdcat.online BS Nursing
Jun 6, 2026

49. A patient with newly diagnosed Type 2 Diabetes Mellitus has elevated fasting blood glucose and insulin resistance. What is the technical pathophysiological defect primarily responsible for insulin resistance?

A. Autoimmune destruction of pancreatic beta cells.
B. Decreased insulin production.
C. Impaired cellular response to insulin, leading to inadequate glucose uptake by peripheral tissues.
D. Excess glucagon secretion.
nmdcat.online BS Nursing
Jun 6, 2026

47. A patient with untreated hypertension develops left ventricular hypertrophy. What is the technical pathophysiological consequence of long-standing hypertension on the heart?

A. Dilation of the left ventricle.
B. Increased afterload, leading to compensatory hypertrophy of the left ventricle.
C. Valvular stenosis.
D. Increased cardiac output.
nmdcat.online BS Nursing
Jun 6, 2026

46. A patient with chronic bronchitis is characterized by a “blue bloater” appearance (cyanosis, edema). What is the technical primary pathophysiological cause of these features?

A. Alveolar destruction and air trapping.
B. Chronic inflammation of the bronchi, leading to mucus hypersecretion, airway obstruction, and hypoxemia/hypercapnia.
C. Reversible bronchospasm.
D. Pulmonary fibrosis.
nmdcat.online BS Nursing
Jun 6, 2026

45. A patient with severe sepsis develops disseminated intravascular coagulation (DIC). What is the critical clinical urgency in managing DIC?

A. Administering large volumes of intravenous fluids.
B. Promptly treating the underlying cause of sepsis and managing bleeding/thrombosis.
C. Performing immediate surgery.
D. Providing only symptomatic relief.
nmdcat.online BS Nursing
Jun 6, 2026

43. A patient with acute myocardial infarction (MI) is given aspirin. From a medicinal perspective, what is the technical pathophysiological mechanism of aspirin in this context?

A. Increases blood pressure.
B. Inhibits platelet aggregation and thrombus formation.
C. Directly dilates coronary arteries.
D. Increases myocardial contractility.
nmdcat.online BS Nursing
Jun 6, 2026

42. A patient with osteoarthiritis experiences joint pain and stiffness, especially with movement, worsening over the day. From a technical pathophysiological perspective, osteoarthritis is characterized by:

A. Autoimmune inflammation of the synovial membrane.
B. Degeneration of articular cartilage.
C. Deposition of uric acid crystals.
D. Bacterial infection of the joint.
nmdcat.online BS Nursing
Jun 6, 2026

41. A patient with liver cirrhosis develops hepatic encephalopathy, characterized by confusion, asterixis, and altered mental status. What is the technical primary pathophysiological mechanism causing this complication?

A. Accumulation of glucose in the brain.
B. Impaired detoxification of ammonia and other neurotoxins by the liver.
C. Cerebral ischemia.
D. Electrolyte imbalance.
nmdcat.online BS Nursing
Jun 6, 2026

40. A patient with acute kidney injury develops hyperkalemia. What is the urgent clinical concern and critical pathophysiological consequence of severe hyperkalemia?

A. Hypoglycemia.
B. Cardiac arrhythmias and potential cardiac arrest.
C. Hypotension.
D. Metabolic alkalosis.
nmdcat.online BS Nursing
Jun 6, 2026
nmdcat.online BS Nursing
Jun 6, 2026
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